孙际宾
2005年 德国GBF基金会优秀博士论文奖
2008年 中国科学院人才计划入选者
2014年 中国产学研合作创新成果奖
2014年 中国产学研合作促进奖
2015年 天津市劳动模范
2016年 政府特殊津贴专家
2019年 中国粮油学会科学技术奖特等奖
2019年 中国科学院科技促进发展奖
2020年 内蒙古自治区科学技术奖一等奖
发表论文150余篇,申请中国发明专利120余项,已授权73项,PCT专利16项,美日等国授权12项。
https://orcid.org/0000-0002-0208-504X
https://scholar.google.com/citations?user=cMJWDh4AAAAJ
https://www.scopus.com/authid/detail.uri?authorId=7410371501
近期代表性论著:
1. Zheng X, Guo Y, Chen M, Lu Y, Du Y, Lei Y, Zheng P*, Sun J*. 2025. Promoter engineering with programmable upstream activating sequences in Aspergillus niger cell factory. Microb Cell Fact 24: 20.
2. Liu J, Zhao XJ, Cheng HJ, Guo YM, Ni XM, Wang LX, Sun GN, Wen X, Chen JZ, Wang J, An JJ, Guo X, Shi ZK, Li HR, Wang RY, Zhao MQ, Liao XP, Wang Y, Zheng P, Wang M, Sun JB. 2025. Comprehensive screening of industrially relevant components at genome scale using a high-quality gene overexpression collection of Corynebacterium glutamicum. Trends in Biotechnology 43: 220-247.
3. Zhang Z, Zhang C, Zhang X, Chen J, Cai N, Zhong S, Han Z, Zhu Y*, Zheng P*, Sun J*, Liu C. 2024. Automated and integrated ultrahigh throughput screening for industrial strain enabled by acoustic-droplet-ejection mass spectrometry. J Pharm Anal 14: 100949.
4. Cao Q*, Han M, Zhang Z, Yu C, Xu L, Shi T, Zheng P, Sun J*. 2023. Novel 15N Metabolic Labeling-Based Large-Scale Absolute Quantitative Proteomics Method for Corynebacterium glutamicum. Anal Chem 95: 4829-4833.
5. Zheng X, Zheng P*, Zhang K, Cairns TC, Meyer V, Sun J*, Ma Y. 2019. 5S rRNA Promoter for Guide RNA Expression Enabled Highly Efficient CRISPR/Cas9 Genome Editing in Aspergillus niger. ACS Synth Biol 8: 1568-1574.
6. Tong Z, Zheng X, Tong Y, Shi YC, Sun J*. 2019. Systems metabolic engineering for citric acid production by Aspergillus niger in the post-genomic era. Microb Cell Fact 18: 28.
7. Cairns TC, Zheng X, Zheng P, Sun J, Meyer V. 2019. Moulding the mould: understanding and reprogramming filamentous fungal growth and morphogenesis for next generation cell factories. Biotechnol Biofuels 12: 77.
8. Wang Y, Liu Y, Liu J, Guo Y, Fan L, Ni X, Zheng X, Wang M*, Zheng P*, Sun J*, Ma Y. 2018. MACBETH: Multiplex automated Corynebacterium glutamicum base editing method. Metab Eng 47: 200-210.
9. Tuyishime P, Wang Y, Fan L, Zhang Q, Li Q, Zheng P*, Sun J*, Ma Y. 2018. Engineering Corynebacterium glutamicum for methanol-dependent growth and glutamate production. Metab Eng 49: 220-231.
10. Fang H, Li D, Kang J, Jiang P, Sun J, Zhang D*. 2018. Metabolic engineering of Escherichia coli for de novo biosynthesis of vitamin B(12). Nat Commun 9: 4917.
11. Zhang YP*, Sun J, Ma Y*. 2017. Biomanufacturing: history and perspective. J Ind Microbiol Biotechnol 44: 773-784.
12. Liu J, Wang Y, Lu Y, Zheng P*, Sun J*, Ma Y. 2017. Development of a CRISPR/Cas9 genome editing toolbox for Corynebacterium glutamicum. Microb Cell Fact 16: 205.
13. Song YF, Nikoloff JM, Fu G, Chen JQ, Li QG, Xie NZ, Zheng P, Sun JB, Zhang DW*. 2016. Promoter Screening from in Various Conditions Hunting for Synthetic Biology and Industrial Applications. Plos One 11: e0158447.
14. Zhang YH*, Sun J, Zhong JJ. 2010. Biofuel production by in vitro synthetic enzymatic pathway biotransformation. Curr Opin Biotechnol 21: 663-669.
15. Lu X, Sun JB, Nimtz M, Wissing J, Zeng AP, Rinas U*. 2010. The intra- and extracellular proteome of growing on defined medium with xylose or maltose as carbon substrate. Microbial Cell Factories 9: 1-13.
16. Wortman JR, Gilsenan JM, Joardar V, Deegan J, Clutterbuck J, Andersen MR, Archer D, Bencina M, Braus G, Coutinho P, von Dohren H, Doonan J, Driessen AJ, Durek P, Espeso E, Fekete E, Flipphi M, Estrada CG, Geysens S, Goldman G, de Groot PW, Hansen K, Harris SD, Heinekamp T, Helmstaedt K, Henrissat B, Hofmann G, Homan T, Horio T, Horiuchi H, James S, Jones M, Karaffa L, Karanyi Z, Kato M, Keller N, Kelly DE, Kiel JA, Kim JM, van der Klei IJ, Klis FM, Kovalchuk A, Krasevec N, Kubicek CP, Liu B, Maccabe A, Meyer V, Mirabito P, Miskei M, Mos M, Mullins J, Nelson DR, Nielsen J, Oakley BR, Osmani SA, Pakula T, Paszewski A, Paulsen I, Pilsyk S, Pocsi I, Punt PJ, Ram AF, Ren Q, Robellet X, Robson G, Seiboth B, van Solingen P, Specht T, Sun J, Taheri-Talesh N, Takeshita N, Ussery D, vanKuyk PA, Visser H, van de Vondervoort PJ, de Vries RP, Walton J, Xiang X, Xiong Y, Zeng AP, Brandt BW, Cornell MJ, van den Hondel CA, Visser J, Oliver SG, Turner G. 2009. The 2008 update of the Aspergillus nidulans genome annotation: a community effort. Fungal Genet Biol 46 Suppl 1: S2-13.
17. Seidl V, Song L, Lindquist E, Gruber S, Koptchinskiy A, Zeilinger S, Schmoll M, Martinez P, Sun J, Grigoriev I, Herrera-Estrella A, Baker SE, Kubicek CP*. 2009. Transcriptomic response of the mycoparasitic fungus Trichoderma atroviride to the presence of a fungal prey. BMC Genomics 10: 567.
18. Qin J, Zhao B, Wang X, Wang L, Yu B, Ma Y, Ma C, Tang H, Sun J, Xu P*. 2009. Non-sterilized fermentative production of polymer-grade L-lactic acid by a newly isolated thermophilic strain Bacillus sp. 2-6. PLoS One 4: e4359.
19. Flipphi M, Sun J, Robellet X, Karaffa L, Fekete E, Zeng AP, Kubicek CP*. 2009. Biodiversity and evolution of primary carbon metabolism in Aspergillus nidulans and other Aspergillus spp. Fungal Genet Biol 46 Suppl 1: S19-S44.
20. Pel HJ, de Winde JH, Archer DB, Dyer PS, Hofmann G, Schaap PJ, Turner G, de Vries RP, Albang R, Albermann K, Andersen MR, Bendtsen JD, Benen JA, van den Berg M, Breestraat S, Caddick MX, Contreras R, Cornell M, Coutinho PM, Danchin EG, Debets AJ, Dekker P, van Dijck PW, van Dijk A, Dijkhuizen L, Driessen AJ, d'Enfert C, Geysens S, Goosen C, Groot GS, de Groot PW, Guillemette T, Henrissat B, Herweijer M, van den Hombergh JP, van den Hondel CA, van der Heijden RT, van der Kaaij RM, Klis FM, Kools HJ, Kubicek CP, van Kuyk PA, Lauber J, Lu X, van der Maarel MJ, Meulenberg R, Menke H, Mortimer MA, Nielsen J, Oliver SG, Olsthoorn M, Pal K, van Peij NN, Ram AF, Rinas U, Roubos JA, Sagt CM, Schmoll M, Sun J, Ussery D, Varga J, Vervecken W, van de Vondervoort PJ, Wedler H, Wosten HA, Zeng AP, van Ooyen AJ, Visser J, Stam H. 2007. Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88. Nat Biotechnol 25: 221-231.
21. Zheng P, Wereath K, Sun JB, van den Heuvel J, Zeng AP*. 2006. Overexpression of genes of the dha regulon and its effects on cell growth, glycerol fermentation to 1,3-propanediol and plasmid stability in. Process Biochemistry 41: 2160-2169.
22. Sun JB, Daniel R, Wagner-Döbler I*, Zeng AP*. 2004. Is autoinducer-2 a universal signal for interspecies communication : a comparative genomic and phylogenetic analysis of the synthesis and signal transduction pathways. Bmc Evolutionary Biology 4: 1-11.
23. Wang W, Sun J, Hartlep M, Deckwer WD, Zeng AP*. 2003. Combined use of proteomic analysis and enzyme activity assays for metabolic pathway analysis of glycerol fermentation by Klebsiella pneumoniae. Biotechnol Bioeng 83: 525-536.
24. Sun J, van den Heuvel J, Soucaille P, Qu Y, Zeng AP*. 2003. Comparative genomic analysis of dha regulon and related genes for anaerobic glycerol metabolism in bacteria. Biotechnol Prog 19: 263-272.
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