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  青年创新促进会成员
 
姓名  
郑迎迎
性别  
专家类别  
N/A
职称  
副研究员
学历  
博士
电话  
022-24828704
传真  
N/A
电子邮件  
zheng_yy(AT)tib.cas.cn
地址  
天津空港经济区西七道32号
邮编  
300308

简历

1、教育经历 

2000.9-2004.7,南京理工大学,高分子材料与工程,学士 

2004.9-2006.7,南京理工大学,生物化工,硕士 

2006.9-2010.7,中国科学院微生物研究所,微生物学,博士 

2007.10-2008.9,德国不莱梅国际大学,生物化学,联合培养   

2、工作经历 

2010.9-2014.4,中国科学院天津工业生物技术研究所,助理研究员 

2014.5至今,中国科学院天津工业生物技术研究所,副研究员 


研究方向:
  

利用蛋白质晶体结构解析的技术手段研究蛋白结构功能关系,主要研究对象为:工业酶、抗生素合成途径中关键蛋白、嗜热菌代谢途径中关键蛋白。 


承担科研项目情况:
  国家自然科学基金青年基金——厌氧菌氧还感应蛋白RSP结构与功能的研究

获奖及荣誉:
  

代表论著:

  1、论文 

  [1] ZHENG Yingying, XUE Yanfen, ZHANG Yueling, ZHOU Cheng, Ulrich Schwaneberg, MA Yanhe. Cloning, expression, and characterization of a thermostable glucoamylase from Thermoanaerobacter tengcongensis MB4 [J]. Applied Microbiology and Biotechnology, 2010,  87(1): 225-233 

  [2] ZHENG Yingying, HUANG Chun-Hsiang, LIU Wenting, KO Tzu-Ping, XUE Yanfen, ZHOU Cheng, GUO Rey-Ting, MA Yanhe. Crystal structure and substrate-binding mode of a novel pectate lyase from Alkaliphilic Bacillus sp. N16-5 [J]. Biochemical and Biophysical Research Communications, 2012, 420(2): 269-274 

  [3] HU Yumei, JIA SREN FeifeiHUANG Chun-HsiangKO Tzu-PingD. A. MitchellGUO Rey-Ting and ZHENG Yingying*. Crystallization and preliminary X-ray diffraction analysis of YisP protein from Bacillus subtilis subsp. subtilis strain 168 [J]. Acta Cryst F., 2013, 69: 77-79  

  [4] RAO Lang, XUE Yanfen, ZHENG Yingying, LV Jianren, MA Yanhe. A Novel Alkaliphilic Bacillus Esterase Belongs to the 13th Bacterial Lipolytic Enzyme Family [J]. PLOS ONE, 2013, 8(4): e60645 

  [5] Xu Jianyong, REN FeifeiHUANG Chun-HsiangZHENG Yingying, ZHEN Jie, SUN Hong, KO Tzu-Ping, HE Miao, CHEN Chun-Chi, CHAN Hsiu-Chien, GUO Rey-Ting, SONG Hui and MA Yanhe. Functional and structural studies of pullulanase from Anoxybacillus sp. LM18-11 [J]. Proteins, DOI: 10.1002/prot.24498 

  [6] SHANG Na, LI Qian, KO Tzu-Ping, CHAN Hsiu-Chien, ZHENG Yingying, HUANG Chun-Hsiang, REN Feifei, CHEN Chun-Chi, ZHU Zhen, Galizzi M, Rodrigues-Poveda CA, Gonzalez-Pacanowska D, Veiga-Santos P, de Carvalho TM, de Souza W, Urbina JA, Wang AH, Docampo R, Oldfield E, GUO Rey-Ting. Squalene synthase as a target for chagas disease therapeutics [J].PLoS Pathog, 2014, 10(5) :e1004114 

  [7] CHAN Hsiu-Chien, FENG Xinxin, KO Tzu-Ping, HUANG Chun-Hsiang, HU Yumei, ZHENG Yingying, Bogue S, Nakano C, Hoshino T, ZHANG Lilan, LV Pin, LIU Wenting, Crick DC, Oldfield E, GUO Rey-Ting. Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis [J]. J Am Chem Soc, 2014, 136(7):2892-6 

  [8] HUANG Chun-Hsiang, KO Tzu-Ping, CHEN Chun-Chi, ZHENG Yingying, CHAN Hsiu-Chien, PANG Xuefei, Wiegel J, SHAO Weilan, GUO Rey-Ting. The substrate/product-binding modes of a novel GH120 β-xylosidase (XylC) from Thermoanaerobacterium saccharolyticum JW/SL-YS485 [J]. Biochem J, 2012, 448(3) :401-7  

  2专著中析出文献 

[1] 郑迎迎,郭瑞庭. 植酸酶的性质、应用和三维结构[C]. 中国科学院生命科学与生物技术局. 2011工业生物技术发展报告. 北京:科学出版社,2011:70-83    

  3、申请专利 

[1] 马延和  郑迎迎  薛燕芬. 一种葡萄糖淀粉酶及其编码基因与应用:中国,200910091269[P].2009-8-14